A shuttle accident leads to Spock's Vulcan DNA being removed by aliens, making him fully Human and completely unprepared to face T'Pring's family during an important ceremonial dinner.

Anson Mount (Captain Christopher Pike)
Ethan Peck (Lieutenant Spock)
Jess Bush (Nurse Christine Chapel)
Christina Chong (Lt. La'an Noonien-Singh)
Celia Rose Gooding (Ensign Nyota Uhura)
Melissa Navia (Lt. Erica Ortegas)
Babs Olusanmokun (Dr. Joseph M'Benga)
Rebecca Romijn (Lt. Commander Una Chin-Riley)

Mia Kirshner (Amanda Grayson)
Michael Benyaer (Sevet)
Dan Jeannotte (Lt. Samuel Kirk)
Ellora Patniak (T'Pril)
Gia Sandhu (T'Pring)

Anjuli Cain (Yellow/Blue)
Alex Kapp (U.S.S. Enterprise Computer)
Ryan Taerk (Durik)

• This is the first appearance of Mia Kirshner as Spock's mother, Amanda Grayson, on Strange New Worlds. She was last seen in the Star Trek: Discovery Season 2 finale "Such Sweet Sorrow, Part 2".